Dual agonist
Tirzepatide
Studied in Phase 3 trials for up to 22.5% body-weight reduction
Average weight loss
SURMOUNT-1 Phase 3 Trial
Flat $35 tracked shipping20mg per vial
$92 USD
Add 2 more, unlock 19%
Single vials are sold out. Tirzepatide is available in the Lumen research stack. See the stack
| Test | Result | Verdict |
|---|---|---|
| Purity, HPLC | 99.31% | PASS |
| Identity, LC-MS | Confirmed | PASS |
| Sterility | No growth | PASS |
| Endotoxin | <1 EU/Vial | PASS |
| Heavy metals + fentanyl | Not detected | PASS |
Shipping, delivery and guarantee terms
- Shipping
- Flat $35, tracked worldwide to supported markets
- Delivery
- 5 to 10 business days, guaranteed
- Payment
- Card, bank transfer, or crypto · All sales final except a purity failure
- Included
- 60-day money-back guarantee · Third-party batch COA
The short answer
What is tirzepatide?
Tirzepatide is a dual GIP and GLP-1 receptor agonist studied as a once-weekly peptide for weight loss. In the Phase 3 SURMOUNT-1 trial, the 15 mg arm reached a group mean of up to about 22.5 percent body-weight reduction over 72 weeks (Jastreboff et al., NEJM 2022). The brand drug is FDA-approved as Mounjaro and Zepbound; research-grade tirzepatide, including ours, is not an approved medicine and is sold for research purposes only.
For what the trials actually used, see the tirzepatide dosage schedule and the results timeline measured over 72 weeks.
Comparing the GLP-1 class
How does retatrutide compare with semaglutide and tirzepatide?
Semaglutide is a single GLP-1 receptor agonist, tirzepatide a GIP and GLP-1 dual agonist, and retatrutide a triple agonist adding glucagon. The three were measured in separate trials with different designs and populations, never head to head, so the honest comparison is trial by trial rather than a ranking. Two research-based comparisons:
Retatrutide vs Ozempic
How the two compare, by mechanism and trial data.
Retatrutide vs Tirzepatide
Where the newer triple-agonist differs from the dual.
Ozempic, Wegovy, and Mounjaro are FDA-approved medications. Research-grade peptides, including ours, are not FDA-approved and are sold for research purposes only. This is education, not medical advice or a treatment claim.
The Science
Dual-Agonist Technology
Tirzepatide activates two metabolic receptor pathways: GLP-1 and GIP. Whether that dual mechanism outperforms a single agonist has not been settled by a head-to-head obesity trial in the published record; the comparisons available come from separate trials.
GLP-1 Receptor
Appetite Suppression
GLP-1 receptor signaling is described as reducing hunger signaling, increasing satiety and slowing gastric emptying.
GIP Receptor
Fat Metabolism
GIP receptor signaling is described as modulating insulin sensitivity, lipid handling and glucose control.
Clinical Data
Clinical Trial Results
22.5%
Mean body-weight reduction, 15 mg arm
SURMOUNT-1, 72 weeks
89%
Achieved 5%+ Loss
of participants
2,539
Trial Participants
SURMOUNT-1
Data from SURMOUNT-1 Phase 3 clinical trial, published in The New England Journal of Medicine. Results represent participants receiving the 15mg maintenance dose. Individual results may vary.
A Well-Studied Compound
The brand drug tirzepatide is FDA-approved as Mounjaro (for Type 2 diabetes) and Zepbound (for weight management); research-grade tirzepatide, including ours, is not an FDA-approved product. The compound has been studied in clinical trials with over 20,000 participants, with reported side effects documented across those trials.
Doses as studied
What doses did the tirzepatide trials study?
SURMOUNT-1 tested three once-weekly maintenance doses, 5 mg, 10 mg, and 15 mg, against placebo over 72 weeks, with each arm reached by gradual step-up from a low starting dose (Jastreboff et al., NEJM 2022). The dosing chart below is a record of what that trial measured, not a target for any one person.
| Once-weekly maintenance dose | Reported mean weight change at 72 weeks | Source |
|---|---|---|
| Placebo | about -3 percent | Jastreboff et al., NEJM 2022 |
| 5 mg | about -15 percent | Jastreboff et al., NEJM 2022 |
| 10 mg | about -19.5 percent | Jastreboff et al., NEJM 2022 |
| 15 mg | up to about -22.5 percent | Jastreboff et al., NEJM 2022 |
The trials reported these doses in milligrams. When a lyophilized vial is reconstituted, the reading in units on a syringe depends on how much bacteriostatic water is added, which is a concentration calculation rather than a dose. The reconstitution calculator does that math, and the tirzepatide dosage page covers the step-up schedule the studies used. How a compound is administered is a question for a licensed clinician.
Comparison
Semaglutide vs tirzepatide: how do they compare?
Tirzepatide is a dual GIP and GLP-1 receptor agonist; semaglutide is a single GLP-1 agonist. Across separate Phase 3 obesity trials, semaglutide reached about 15 percent mean body-weight reduction in STEP 1 (Wilding et al., NEJM 2021) and tirzepatide reached up to about 22.5 percent in SURMOUNT-1 (Jastreboff et al., NEJM 2022).
| Compound | Receptor targets | Top reported weight loss | Source |
|---|---|---|---|
| Semaglutide | GLP-1 | about 15 percent | Wilding et al., NEJM 2021 |
| Tirzepatide | GIP and GLP-1 | up to about 22.5 percent | Jastreboff et al., NEJM 2022 |
Those numbers come from different trials with different designs and populations, so the gap between them is not a measured head-to-head difference. The one direct comparison, SURPASS-2, was run in adults with type 2 diabetes rather than obesity and reported larger reductions in blood sugar and body weight with tirzepatide (Frías et al., NEJM 2021). For the dose-by-dose picture, see tirzepatide vs Ozempic and semaglutide dosage.
Compounded, brand, research-grade
What is compounded tirzepatide?
Tirzepatide reaches people in three different forms that are not interchangeable. The brand drug is FDA-approved under two names: Mounjaro, for type 2 diabetes, and Zepbound, for weight management. Compounded tirzepatide is prepared by licensed compounding pharmacies and dispensed on a prescription, a channel that saw wide use during the branded shortage, and it is a different regulatory category from the brand product.
Research-grade tirzepatide, including ours, is laboratory material sold for research purposes only. It is not an approved medicine, not a compounded prescription, and not a branded drug. For how the three differ, see the compounded tirzepatide explainer.
Research Timeline
What the studies measured, and when
Research Timeline
What the studies measured, and when
Research timeline
What the studies measured, and when
The trial
SURMOUNT-1 tested three once-weekly maintenance doses, 5 mg, 10 mg and 15 mg, against placebo over 72 weeks (Jastreboff et al., NEJM 2022; doi:10.1056/NEJMoa2206038; PMID 35658024).
Escalation
Each arm was reached by gradual escalation rather than started at its maintenance dose, which is the standard approach for reducing early gastrointestinal effects in this class.
72 weeks
The 15 mg arm reached up to about 22.5 percent mean weight loss, with smaller reductions at 10 mg and 5 mg (Jastreboff et al., 2022).
Approval status
The brand drug is FDA-approved as Mounjaro and Zepbound. Research-grade tirzepatide, including ours, is not an approved medicine.
Your Kit
What's Included
$92 USD
Flat $35 shipping · All sales final
Single vials are sold out. Tirzepatide is available in the Lumen research stack. See the stack
Tirzepatide 20mg Vial
20mg per vial · Lyophilized powder, sealed vial
Study Protocol Reference
Educational ranges and titration schedules reported in published studies. Not a prescription; consult a licensed physician.
Worldwide Shipping
5 to 10 business days, guaranteed
Ongoing order support
Direct team access
Your kit includes the vials and bacteriostatic water. Insulin syringes ship to select delivery regions; where they can't ship, we send a same-day sourcing link. A printed reference guide ships with every order.
Traveling with your order
Freeze-dried vials travel well; reconstituted vials travel cold. Rules vary by country. Share your dates when you order.
Why your vials arrive plain
Unlabeled on purpose: discreet, and standard for research-grade material. Match a batch to its certificate with your order number. See the COA page.
Verified orders
What buyers said about their Tirzepatide order
5.00 · 12 reviews from orders containing this vial. Published word for word.
i had been burned by a supplier who shipped the wrong strength last year and this time everything matched exactly what was on my order confirmation. no confusion, no back and forth over what should have arrived versus what actually did
Tam - Hue
Verified order · Tirzepatide, CJC-1295 / Ipamorelin · Aug 07, 2026
this was my second run through and honestly the packaging barely changed between orders in a good way, same tray layout, same tape placement down to the millimeter. whatever process they have running is clearly not improvised week to week
Anon - Boise, ID
Verified order · Tirzepatide, MOTS-c · Jul 26, 2026
i was planning to wait one more month before trying a new supplier but a sister in a group chat mentioned them and the timing just worked out better than expected. first order went through cleanly with nothing missing from what was listed
Kai - Hoi An
Verified order · Tirzepatide · Jul 21, 2026
arrived wednesday which i think was slightly ahead of the quoted window but i am not going to quibble about it. box was flat and undamaged, tape job straight down the middle like a factory seal rather than someone just slapping three strips on crookedly
Anon - Cần Thơ
Verified order · Retatrutide, Tirzepatide · Jul 11, 2026
i had put this on my list to try for a while and only got around to ordering when a colleague at work mentioned they had already been through two rounds. the timing worked out fine and nothing about the first delivery was off in any way
Lan - Da Nang
Verified order · Tirzepatide, CJC-1295 / Ipamorelin · Jul 04, 2026
second order now and what stood out this time was the insert card. last one had my street number off by two digits which i only caught because i double checked before binning it, this one is spot on. small thing but it tells me someone actually proofed things instead of just hitting send
Noor - Las Vegas, NV
Verified order · Tirzepatide · Jun 20, 2026
Our Guarantee
We Stand Behind Our Quality.
Peptara Labs supplies research-grade Tirzepatide. The brand drugs Mounjaro and Zepbound are FDA-approved; research-grade tirzepatide, including ours, is not an FDA-approved product. We stand behind our product quality, verified by a certificate of analysis on every batch.
60-Day Money Back Guarantee
Test it at any lab, or your money back
Send any vial to an independent lab within 60 days of delivery. If it does not test as stated on its certificate of analysis (COA), or your order was not handled correctly, you get a full refund. The 60 days is your window to verify us, not a shelf life. The guarantee is on product quality, never on a health outcome.
Study Protocol Reference, Included
Every order includes a written reference to the dose ranges published studies used, with the study named, plus support at no extra cost. This is not a prescription; consult a licensed physician.
Direct WhatsApp Access
Every order includes direct access to our support team. Questions about certificates, reconstitution, storage, shipping or an order, message us any time and a real person responds.
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Customers served
Consistently rated by our customers
Quality guarantee: full refund on any purity failure. All sales otherwise final. The 60-day money back guarantee covers product purity, certificate of analysis, and fulfillment. It is not conditioned on any outcome and does not promise one. This is educational information, not medical advice; consult a licensed physician.
Also in a stack
Tirzepatide is in a research stack
A stack groups catalog compounds from one research area and is priced at 35 percent off their combined retail. It is a grouping for browsing related research, not a protocol, and no stack has been tested as a combination.
Lumen stack
Weight & body composition research
Tirzepatide ×2, BPC-157, GHK-Cu, Glutathione
Research and citations
Peer-reviewed sources
- Jastreboff AM, et al. (2022). Tirzepatide Once Weekly for the Treatment of Obesity (SURMOUNT-1). New England Journal of Medicine. doi.org/10.1056/NEJMoa2206038
- Aronne LJ, et al. (2024). Continued Treatment With Tirzepatide for Maintenance of Weight Reduction in Adults With Obesity (SURMOUNT-4). JAMA. doi.org/10.1001/jama.2023.24945
Citations refer to the peer-reviewed publications these figures are taken from. Every dose range reported on this site is the range a named study used. Not a substitute for medical advice.
Explore more
Related guides, comparisons, and compounds studied for related endpoints
Where to buy tirzepatide
The prescription and research-grade lanes, and what to verify before buying.
Compounded tirzepatide explained
How compounded, brand, and research-grade tirzepatide differ.
Tirzepatide price per vial
Full cost breakdown per vial and per mg, plus email-signup pricing.
Tirzepatide complete guide
Dual-agonist mechanism, SURMOUNT data, titration in units, and stacking.
Tirzepatide vs Retatrutide
Dual-agonist (brand drug FDA-approved) vs triple-agonist maximum studied effect.
Tirzepatide vs Ozempic
22% vs 15% fat loss, and the cost difference.
Best peptides for fat loss
How Tirzepatide ranks by trial effect size.
Reconstitution calculator
Concentration math for a lyophilized vial, in units rather than mL.
BPC-157
Stack pair for joint and gut support during a cut.
Tirzepatide dosage
What the SURMOUNT trials used, in units not mL.
Tirzepatide side effects
Reported effects and how often they occurred.
Tirzepatide results timeline
What the trials measured week by week.
Tirzepatide half-life
Why it is a once-weekly compound.
Tirzepatide for weight loss
The SURMOUNT-1 fat-loss data in plain terms.
Semaglutide dosage
What the STEP trials used for the single GLP-1 agonist, in units not mL.
Retatrutide
The triple agonist (GIP, GLP-1 and glucagon), the maximum studied effect in the class.
Tirzepatide FAQ
Order Tirzepatide, 20mg vial
Order Tirzepatide today. Worldwide shipping, 5 to 10 business days, guaranteed.
Single vials are sold out. Tirzepatide is available in the Lumen research stack. See the stack
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